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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RNF168
All Species:
13.64
Human Site:
S414
Identified Species:
30
UniProt:
Q8IYW5
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IYW5
NP_689830.2
571
65020
S414
R
R
K
V
S
P
E
S
S
P
D
Q
E
E
T
Chimpanzee
Pan troglodytes
XP_001164756
571
65044
S414
R
R
K
M
S
P
E
S
S
P
D
Q
E
E
T
Rhesus Macaque
Macaca mulatta
XP_001098468
146
16847
V26
C
T
D
D
C
Q
P
V
R
L
L
S
K
P
G
Dog
Lupus familis
XP_545152
570
65205
S414
R
K
K
F
P
K
A
S
S
D
Q
E
E
T
E
Cat
Felis silvestris
Mouse
Mus musculus
Q80XJ2
565
64761
S414
R
K
I
F
I
E
S
S
S
D
Q
E
E
T
E
Rat
Rattus norvegicus
B2RYR0
564
64386
S413
R
R
K
I
F
I
T
S
S
L
D
Q
E
E
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519147
409
45328
L289
K
Q
E
E
E
D
R
L
L
A
L
Q
L
Q
R
Chicken
Gallus gallus
XP_001233498
605
68577
T414
K
P
E
S
L
P
N
T
K
E
A
P
K
R
K
Frog
Xenopus laevis
Q6INS5
557
62872
E414
V
H
A
G
K
L
I
E
L
E
E
N
L
Y
E
Zebra Danio
Brachydanio rerio
Q7T308
474
53229
W354
E
E
A
L
R
S
R
W
Q
Q
E
E
E
D
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_393681
789
90729
Y548
H
I
R
N
G
M
V
Y
L
K
I
T
R
R
D
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
22.5
76.5
N.A.
63.9
64
N.A.
29
43.4
39.7
34.3
N.A.
N.A.
21.2
N.A.
N.A.
Protein Similarity:
100
99.6
24.5
84.2
N.A.
75.3
74.9
N.A.
43.2
56.8
55.8
51.1
N.A.
N.A.
41.1
N.A.
N.A.
P-Site Identity:
100
93.3
0
33.3
N.A.
26.6
66.6
N.A.
6.6
6.6
0
6.6
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
100
100
6.6
46.6
N.A.
40
73.3
N.A.
33.3
33.3
6.6
33.3
N.A.
N.A.
6.6
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
19
0
0
0
10
0
0
10
10
0
0
0
0
% A
% Cys:
10
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
10
10
0
10
0
0
0
19
28
0
0
10
10
% D
% Glu:
10
10
19
10
10
10
19
10
0
19
19
28
55
28
28
% E
% Phe:
0
0
0
19
10
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
10
10
0
0
0
0
0
0
0
0
0
10
% G
% His:
10
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
10
10
10
10
10
10
0
0
0
10
0
0
0
0
% I
% Lys:
19
19
37
0
10
10
0
0
10
10
0
0
19
0
10
% K
% Leu:
0
0
0
10
10
10
0
10
28
19
19
0
19
0
0
% L
% Met:
0
0
0
10
0
10
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
10
0
0
10
0
0
0
0
10
0
0
0
% N
% Pro:
0
10
0
0
10
28
10
0
0
19
0
10
0
10
0
% P
% Gln:
0
10
0
0
0
10
0
0
10
10
19
37
0
10
0
% Q
% Arg:
46
28
10
0
10
0
19
0
10
0
0
0
10
19
19
% R
% Ser:
0
0
0
10
19
10
10
46
46
0
0
10
0
0
0
% S
% Thr:
0
10
0
0
0
0
10
10
0
0
0
10
0
19
28
% T
% Val:
10
0
0
10
0
0
10
10
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
10
0
0
0
0
0
10
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _